قد يزيد اضطراب فرط الحركة ونقص الانتباه في مرحلة الطفولة من خطر الإصابة بمشاكل صحية جسدية لاحقاً. من بين هذه المشاكل الصحية، يمكن أن نجد الصداع النصفي، ومشاكل الظهر، والسرطان، والصرع، بالإضافة إلى السكري.
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